The laboratory of Dr. Brian C. Smith is located in the Department of Biochemistry at the Medical College of Wisconsin in Milwaukee, Wisconsin, USA. Our research focuses on signaling pathways involving reversible acetylation and gaseous signaling and how these pathways underlie basic biochemical processes important in inflammation-related diseases such as cancer, heart disease, and Type I diabetes.

We welcome applications from motivated individuals at all scientific levels to join our research team.


August 2019 - The Smith Lab welcomes Research Technologist Steven Summers and rotating IDP graduate student Alyssa Fernandez!

July 2018 - Welcome to postdoc Moua Yang, joining the Smith Lab following completion of his PhD in Roy Silverstein's lab. He will be supported by an NIH T32 training grant through the MCW cardiovascular center.

June 2018 - Welcome to summer students Brad Julga (MSSRP), Nnenna Nwaelugo (SPUR), and Guadalupe Valdivia Esparza (DSHREP)!

April 12, 2018 - IDP graduate student Kelsey Kalous won a poster award at the MCW Redox Biology Symposium.

January 2018 - Welcome to visiting postdoc Zuzana Gulasova from Pavol Jozef Šafárik University in Kosice, Slovakia.

October 2017 - New publication from Brian and Mike of the Smith Lab: "Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4Biochemistry, 2017, 56 (41), pp 5485–5495 

Our summer research program undergraduates were such a great addition to our lab this summer! @mcwspur #DSHREP

Congrats to Moua Yang, PhD '18 on his appointment as a postdoctoral fellow! A great addition to the @briansmithlab! https://t.co/JXD6DtxXkM

Congrats to our postdoc Moua Yang on his receipt of a T32 postdoctoral training fellowship! https://t.co/Z0ZZA46bUo

Believe it or not, I’ll be doing a Q&A on reddit! So get your questions ready for the AMA at https://t.co/ZA8EBtNcq4 this Saturday from 2-4 p.m. central time. I Hope to explain how family, @maccfund @childhealthwi @MedicalCollege & our @Bucks fuel this fan! @BucksOnReddit

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